Support Lampidis 2-DG Cancer Trial
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Professor of Cell Biology at the University of Miami Miller School of Medicine, Dr Theodore Lampidis could just be sitting on one of the holy grails of medicine – a universal treatment for all types of cancer.
Dr. Lampidis has published more than 100 research papers in respected scientific journals, but it is his latest review article, The Wonders of 2-DG, which is causing a stir in the scientific community and receiving rave reviews from his peers around the world. It is a distillation of his life's work into glucose metabolism and its effect on cancerous tumors.
There is an elegant simplicity to Dr. Lampidis’ groundbreaking research which has universal appeal. He is a pioneer in exploring and exploiting the unique usage of glucose in cancer cells using a simple sugar compound called 2-Deoxyglucose (2-DG). His discovery is based on the fact that the cancer cells most resistant to chemotherapy found within the inner core of all solid tumors do not receive enough oxygen (a state known as hypoxia) and therefore must rely exclusively on sugar to survive.
Dr. Lampidis hypothesized he could target these hypoxic tumor cells by feeding them 2-DG and effectively starve them to death. The process of breaking down glucose (glycolysis) is so fundamental, it has survived a billion years of evolution dating back to a time when there was no oxygen in our atmosphere and the only source of energy that could be used to keep tiny microbes alive was sugar.
Dr. Lampidis' eureka moment led to two consecutive five-year awards from the National Cancer Institute, which stated in the reviews of his research that “Dr. Lampidis’ work could eventually lead to cures in certain cancers.”
This led to an FDA-approved Phase I clinical trial to determine the tolerable dose level of 2-DG. The results of the trial (which have recently been published) sets the groundwork for the next Phase II clinical trial, which requires investigating the most effective combination treatments and drug delivery methods.
And that’s where he has hit a roadblock. The unfortunate reality is that since 2-DG cannot be patented, pharmaceutical companies are not interested in devoting their resources to bring this wonder drug to market.
Although the University has been very supportive of his work, resources are limited due to budget cuts and reductions in federal funding from the National Institutes of Health, and from a team of five post graduate researchers in his lab he finds himself left with just one technician.
A dedicated group of volunteers have banded together to raise awareness and funding for Dr Lampidis’ groundbreaking work. And we’re calling on the GoFundMe community to help raise funds for Phase II clinical trials for 2-DG and bring this revolutionary treatment to benefit cancer sufferers world-wide. We are convinced that if 2-DG could be patented, this drug would already be available to cancer sufferers everywhere.
Please join our cause and help us fight the fight in bringing this universal treatment to cancer patients suffering from this devastating disease. For further information visit: www.lampidisfoundation.org .
Dr. Lampidis has published more than 100 research papers in respected scientific journals, but it is his latest review article, The Wonders of 2-DG, which is causing a stir in the scientific community and receiving rave reviews from his peers around the world. It is a distillation of his life's work into glucose metabolism and its effect on cancerous tumors.
There is an elegant simplicity to Dr. Lampidis’ groundbreaking research which has universal appeal. He is a pioneer in exploring and exploiting the unique usage of glucose in cancer cells using a simple sugar compound called 2-Deoxyglucose (2-DG). His discovery is based on the fact that the cancer cells most resistant to chemotherapy found within the inner core of all solid tumors do not receive enough oxygen (a state known as hypoxia) and therefore must rely exclusively on sugar to survive.
Dr. Lampidis hypothesized he could target these hypoxic tumor cells by feeding them 2-DG and effectively starve them to death. The process of breaking down glucose (glycolysis) is so fundamental, it has survived a billion years of evolution dating back to a time when there was no oxygen in our atmosphere and the only source of energy that could be used to keep tiny microbes alive was sugar.
Dr. Lampidis' eureka moment led to two consecutive five-year awards from the National Cancer Institute, which stated in the reviews of his research that “Dr. Lampidis’ work could eventually lead to cures in certain cancers.”
This led to an FDA-approved Phase I clinical trial to determine the tolerable dose level of 2-DG. The results of the trial (which have recently been published) sets the groundwork for the next Phase II clinical trial, which requires investigating the most effective combination treatments and drug delivery methods.
And that’s where he has hit a roadblock. The unfortunate reality is that since 2-DG cannot be patented, pharmaceutical companies are not interested in devoting their resources to bring this wonder drug to market.
Although the University has been very supportive of his work, resources are limited due to budget cuts and reductions in federal funding from the National Institutes of Health, and from a team of five post graduate researchers in his lab he finds himself left with just one technician.
A dedicated group of volunteers have banded together to raise awareness and funding for Dr Lampidis’ groundbreaking work. And we’re calling on the GoFundMe community to help raise funds for Phase II clinical trials for 2-DG and bring this revolutionary treatment to benefit cancer sufferers world-wide. We are convinced that if 2-DG could be patented, this drug would already be available to cancer sufferers everywhere.
Please join our cause and help us fight the fight in bringing this universal treatment to cancer patients suffering from this devastating disease. For further information visit: www.lampidisfoundation.org .
Organizer
Ted Lampidis
Organizer
Miami, FL