Support for Sutton Lauinger and Family

Sutton Lauinger was diagnosed with stage IVB Hodgkin lymphoma, back in 2009 and has battled his cancer off and on for the past 14 years. As of 6/29/23 Sutton has been recently diagnosed with Acute Myeloid Leukemia along with still battling his Hodgkin Lymphoma.

Sutton does have another long road a head of him, which will require many days in the hospital. Sutton is married to Sheena and has a two year old son Conrad. Sutton and his family will face some of their most difficult times financially and personally over these next few months. As their family, we are reaching out to seek help for their family and all the medical expenses they have a head. Sutton will be unable to work for the time being & your support means so much for their family.

Here is Sutton's medical journey since 2009:

Mr. Lauinger is a 34-year-old gentleman who was diagnosed with stage IVB Hodgkin lymphoma, classic type, in June of 2009. He received 6 cycles of ABVD chemotherapy and attained complete remission. He relapsed in July of 2010 when he was treated with salvage chemotherapy with ICE for 2 cycles followed by autologous stem cell transplantation at the Mayo Clinic in April of 2010. Unfortunately he relapsed in March of 2011 in the retroperitoneum and was treated with brentuximab vedotin. Despite initial response, he progressed and was then treated with gemcitabine, cisplatin, and dexamethasone. He then underwent allogeneic transplantation with reduced intensity conditioning and HLA match sibling donor. He received consolidative radiation therapy to the neck, retroperitoneum, and pelvic lymph nodes. Posttransplant he developed severe inflammatory paraplegia, which responded to high-dose steroids and prolonged rehabilitation. He also had severe postradiation proctitis. He then relapsed in June of 2013 with enlarging right inguinal lymphadenopathy. A biopsy was positive for classic Hodgkin lymphoma. He received radiation to the involved right nodes in Fargo with resolution. He then relapsed in December of 2013 in the left groin, again biopsy revealing the same lymphoma. He was then treated with bendamustine. He received 3 cycles, which led to complete remission. He then received a donor lymphocyte infusion in May of 2014. He then relapsed in the summer of 2014 and received radiation therapy with complete resolution in the left groin. Unfortunately he relapsed and then received 6 cycles of chemotherapy with ChIVPP. He then went into complete remission based on the PET/CT scan. Unfortunately, he then developed elevated liver enzymes, which were biopsied and proven to be chronic graft-versus-host disease. He was treated with high-dose steroids. Unfortunately, he relapsed again in early 2016, and was started on immunotherapy with nivolumab in February of 2016. He achieved a good response after an initial flare to the medication. He has noted persistent disease in the right neck, right supraclavicular area, and the right axilla and in the left cervical area. The rest of the disease continued to be in remission. He started radiation therapy to areas of persistent disease on October 4, 2016. Completed radiation in 9/2016. He was admitted to the hospital in 2/2017 with Influenza A and pneumococcal pneumonia. He had respiratory failure. He recovered slowly. Nivolumab was continued. PET/CT scan in 11/2017 did not reveal any clear evidence of recurrent disease. One small right common femoral node which may be related to inflammation. Was started on levothyroxine for elevated TSH in 10/2017. Dose was increased further in 2/2018. PET/CT scan in 9/2018 showed disease progression. He was evaluated for a trial with ruxolitinib and nivolumab at the UoM. He was on study through 5/2019. PET/CT scan showed disease progression. There was some concern of lymphoma in the lungs versus fungal infection. Bronchoscopy and BAL in 6/2019 showed no evidence of fungal infection. Blood tests negative for fungus as well. BAL fluid grew Moraxella which he is currently being treated for with levofloxacin. Started salvage bendamustine on 6/26/2019. He developed a stuffed head and fever. Treated with dual antibiotic therapy. Received 3 cycles of bendamustine with complete resolution of FDG activity on PET/CT scan done in 9/2019. Completed 5 cycles through 10/2019.

He developed itching in 2/2020 and felt that the lymphoma is back. He also hurt his left shin and developed swollen nodes in the groin and tightness in the leg. PET/CT scan on 4/1/2020 revealed multiple new pulmonary nodules/masses, bulky FDG avid left internal and external iliac chain lymphadenopathy and encasement of the distal left ureter and resultant mild to moderate left hydroureteronephrosis. Multiple new FDG avid left upper abdominal lymph nodes, nodules posterior to the descending colon, and within the mesorectal fat consistent with metastases. Large right iliac focus of hypermetabolism suggestive of metastatic disease involvement. Chemotherapy with gemcitabine, oxaliplatin and dexamethasone was discussed with Dr. Bachanova and started on 4/22/2020. Partial response was evident after 3 cycles.

He had COVID-19 on 9/17/2020. He recovered uneventfully. He developed right upper extremity DVT on 9/28/2020. He has been on anticoagulation since that time with apixaban. Received radiation to the pelvis and left inguinal nodal regions in 10/2020 for left hydronephrosis. Started ChlVPP chemotherapy on 12/22/20. Partial response with residual disease in chest noted on PET scan done at UoM.

He was enrolled to FT500 + nivolumab trial at the UoM. NK cells given on 2/2/2021. Had fever and chills from IL-2. Nivolumab started on 2/9/2021. Received two cycles. Had persistent right arm PICC line associated DVT in 3/2021. Completed nivolumab treatment on protocol in 7/2021 and recommendation was to continue nivolumab as he achieved a complete imaging response. Developed right lower lobe pneumonia with S. Aureus and Pseudomonas in 5/2021. Treated with levofloxacin and Bactrim. Also received isovuconazole. Nivolumab was continued. PET/CT scan from 7/2021 and 10/20/2021 compared. It appears that the sensitivity of our PET scanner is higher than UoM. As such it was not clear whether this represented progression, but was concerning. Left ear and left neck nodes were reactive. PET/CT scan in 12/2021 compared with 10/2021 revealed slight progression, but clear progression as compared to 7/2021. Nivolumab was continued.

He has had trouble with a monthly head cold/sinusitis since 3/2022. Was given multiple antibiotics through 10/2022. PET scans revealed gradual worsening of disease over the year. Started ChlVPP chemotherapy in 10/2022. Pegfilgrastim was added after cycle 2. He was admitted with left forearm cellulitis in 12/2022. Completed antibiotic treatment. Wound healed slowly. Chemotherapy was stopped in 12/2022.

Had moderate fatigue. Found to have hypogonadism. Started on testosterone supplements. Anemia persisted. Started on darbepoetin.

Developed worsening itching in early 5/2023. PET scan on 6/16/2023 revealed multiple intrapulmonary lesions, which were increased over the interval. Lesion along the left iliac fossa showed a clear increase in size and degree of uptake. New intra-abdominal soft tissue implants, especially left mid and lower abdomen and adjacent to the rectosigmoid colon. He has had trouble with productive cough and asthma symptoms over the past month.

Thank you in advance from the Lauinger family